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Tick-borne infections are zoonotic—meaning they are passed from animals to humans. “Vectors” like ticks, mosquitos and fleas transmit the diseases from animals like mice, rats, and squirrels to humans when they bite. Ticks can carry many bacteria, viruses, fungi and protozoans all at the same time and transmit them in a single bite. The most common tick-borne diseases in the United States include Lyme Disease, Babesiosis, Anaplasmosis, Ehrlichiosis, Relapsing Fever, Tularemia, Rocky Mountain spotted fever (RMSF). Diseases acquired together like this are called co-infections.


Coinfections may be common – at least among those with chronic Lyme disease. A recently published LDo (Lyme Disease Org) survey of over 3,000 patients with chronic Lyme disease found that over 50% had coinfections, with 30% reporting two or more coinfections. The most common coinfections were Babesia (32%), Bartonella (28%), Ehrlichia (15%), Mycoplasma (15%), Rocky Mountain Spotted Fever (6%), Anaplasma (5%), and Tularemia (1%).


A person with a co-infection generally experiences more severe illness, more symptoms, and a longer recovery. The CDC recommends that physicians consider possible co-infection with Babesia or Anaplasma when patients have more severe symptoms of Lyme disease. However, other co-infections may be present as well.


Since Lyme disease was first identified in 1981, researchers have found more than 15 tick-borne pathogens that weren’t known before. New ones are still being discovered. In 2011, Borrelia Miyamotoi was identified as a cause of disease and recently recognized by the CDC in the United States. Commercial tests are not available for all tick-borne diseases, including infection with B. Miyamotoi or Powassan virus.